NRAMP 1 3 ’ UTR polymorphisms are not associated with natural resistance to 1 Brucella abortus in cattle 2 3 Running title : NRAMP 1 3 ’ UTR polymorphisms and brucellosis in cattle 4 5
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چکیده
Brucella abortus in cattle 2 3 Running title: NRAMP1 3’UTR polymorphisms and brucellosis in cattle 4 5 Tatiane A. Paixão, Fernando P. Poester, Alcina V. Carvalho Neta, Álan M. Borges, 6 Andrey P. Lage, and Renato L. Santos* 7 8 1 Departamento de Clínica e Cirurgia Veterinária, 2 Departamento de Medicina Veterinária 9 Preventiva. Escola de Veterinária, Universidade Federal de Minas Gerais, 31270-901 Belo 10 Horizonte, MG, Brazil. 11 12 * Correspondence: 13 Escola de Veterinária da UFMG, Depto. Clínica e Cirurgia Vet., Av. Antônio Carlos, 6627, 14 31270-901 Belo Horizonte, MG, Brazil. 15 E-mail: [email protected] 16 Fax: 55-31-3499-2230 17 Phone: 55-31-3499-2239 18 AC CE PT ED Copyright © 2007, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved. Infect. Immun. doi:10.1128/IAI.01855-06 IAI Accepts, published online ahead of print on 12 March 2007
منابع مشابه
NRAMP1 3' untranslated region polymorphisms are not associated with natural resistance to Brucella abortus in cattle.
The NRAMP1 gene encodes a divalent cation transporter, located in the phagolysosomal membrane of macrophages, that has been associated with resistance to intracellular pathogens. In cattle, natural resistance against brucellosis has been associated with polymorphisms at the 3' untranslated region (3'UTR) of the NRAMP1 gene, which are detectable by single-strand conformational analysis (SSCA). T...
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